Are E-Cigarettes Harmful to the Heart?
Are e-cigarettes harmful to the heart? Although vaping products are popular, their health effects remain poorly understood. New research has examined the flavoring chemicals used in these products and their impact on cardiovascular health. A new study in
Are e-cigarettes harmful to the heart? Despite the popularity of e-cigarettes, little is known about their health effects. New research has investigated the chemicals used for flavoring these products and their impact on cardiovascular health. A new study on atherosclerosis, thrombosis, and vascular biology concludes that the chemicals used to create these flavors may damage the cells inside blood vessels and the heart.
E-cigarettes were first introduced in the United States in 2006 and marketed as a safer alternative to traditional cigarettes.
These battery-powered devices heat a liquid that is then inhaled by the user. However, e-cigarettes still contain nicotine and some of the chemicals used in regular cigarettes.
Since their introduction, they have become quite popular and are widely used as an alternative to smoking traditional tobacco products. They are often used to help people quit smoking, as they believe this will reduce health risks.
They are also popular among young people. According to data from the Centers for Disease Control and Prevention (CDC), the number of middle and high school students using e-cigarettes increased from 2011 to 2016.
However, the American Heart Association (AHA) does not recommend their use and advises people to avoid these devices. The AHA believes that nicotine-containing e-cigarettes should be regulated by law just like traditional tobacco products.
Impact on the Heart
This new study was led by Dr. Jessica L. Fetterman from Boston University School of Medicine. Dr. Fetterman and her team wanted to test the effects of these chemical additives on blood vessels and the heart.
The researchers observed nine chemicals used to create a range of flavors, including mint, vanilla, banana, burnt flavor, cinnamon, clove, butter, strawberry, and ice cream.
They used three groups of volunteers: one group consisted of non-smokers or non-e-cigarette users, another group included six people who smoked menthol cigarettes, and the last group included six people who did not smoke menthol cigarettes.
Dr. Fetterman and her team studied the short-term effects of e-cigarette flavorings on the cells inside blood vessels, specifically endothelial cells.
Potential Health Impacts
The researchers collected endothelial cells from participants and exposed them to different chemical flavorings. They demonstrated that all flavors damaged the nitric oxide levels in endothelial cells.
However, some flavors caused higher levels of inflammation and led to a more significant reduction in nitric oxide production.
Dr. Fetterman stated, “Increased inflammation and loss of nitric oxide are the first changes leading to cardiovascular disease and conditions such as heart attacks and strokes, so they are considered early predictors of heart disease.”
“Our findings suggest that these flavorings may have serious health implications.”
“Our research and previous studies have provided evidence that flavorings can be toxic in the lungs and cardiovascular system. Flavorings are also a driving factor in youth tobacco use and the continued use of tobacco by smokers.”
— Dr. Jessica L. Fetterman
Dr. Fetterman and her team directly tested the effects of flavorings at levels that the body might reach. However, she also clarified the limitations of the study; for example, they only tested short-term effects, and this study “did not heat all flavorings and did not include other chemicals used in e-cigarettes.”
There is still much to explore; as Dr. Fetterman said, “We still do not know how the concentrations of these flavorings enter the body.”
E-cigarettes were first introduced in the United States in 2006 and marketed as a safer alternative to traditional cigarettes.
These battery-powered devices heat a liquid that is then inhaled by the user. However, e-cigarettes still contain nicotine and some of the chemicals used in regular cigarettes.
Since their introduction, they have become quite popular and are widely used as an alternative to smoking traditional tobacco products. They are often used to help people quit smoking, as they believe this will reduce health risks.
They are also popular among young people. According to data from the Centers for Disease Control and Prevention (CDC), the number of middle and high school students using e-cigarettes increased from 2011 to 2016.
However, the American Heart Association (AHA) does not recommend their use and advises people to avoid these devices. The AHA believes that nicotine-containing e-cigarettes should be regulated by law just like traditional tobacco products.
Impact on the Heart
This new study was led by Dr. Jessica L. Fetterman from Boston University School of Medicine. Dr. Fetterman and her team wanted to test the effects of these chemical additives on blood vessels and the heart.
The researchers observed nine chemicals used to create a range of flavors, including mint, vanilla, banana, burnt flavor, cinnamon, clove, butter, strawberry, and ice cream.
They used three groups of volunteers: one group consisted of non-smokers or non-e-cigarette users, another group included six people who smoked menthol cigarettes, and the last group included six people who did not smoke menthol cigarettes.
Dr. Fetterman and her team studied the short-term effects of e-cigarette flavorings on the cells inside blood vessels, specifically endothelial cells.
Potential Health Impacts
The researchers collected endothelial cells from participants and exposed them to different chemical flavorings. They demonstrated that all flavors damaged the nitric oxide levels in endothelial cells.
However, some flavors caused higher levels of inflammation and led to a more significant reduction in nitric oxide production.
Dr. Fetterman stated, “Increased inflammation and loss of nitric oxide are the first changes leading to cardiovascular disease and conditions such as heart attacks and strokes, so they are considered early predictors of heart disease.”
“Our findings suggest that these flavorings may have serious health implications.”
“Our research and previous studies have provided evidence that flavorings can be toxic in the lungs and cardiovascular system. Flavorings are also a driving factor in youth tobacco use and the continued use of tobacco by smokers.”
— Dr. Jessica L. Fetterman
Dr. Fetterman and her team directly tested the effects of flavorings at levels that the body might reach. However, she also clarified the limitations of the study; for example, they only tested short-term effects, and this study “did not heat all flavorings and did not include other chemicals used in e-cigarettes.”
There is still much to explore; as Dr. Fetterman said, “We still do not know how the concentrations of these flavorings enter the body.”



